The HTLV-1 related endogenous retroviral sequence (HRES-1)/Rab4, also designated as Rab4A, is overexpressed in SLE patients’ T cells [10], and it regulates the expression of CD71 [60,61], CD4 [61], and TCRζ [10]. This evidence concerns the gene RAB4A and systemic lupus erythematosus.