Moreover, in the monocytes of dementia patients, the expression levels of CD163, CD206, and the ratio of CD163/CD206 are lower than those detected in patients without dementia (CD163—3420.37 vs. 2108.14 MFI, p = 0.032; CD206—562.85 vs. 445.58 MFI, p = 0.001; CD163/CD206—9.2 vs. 4.1, p = 0.01). The gene discussed is MRC1; the disease is dementia.