KPF demonstrated a chemoprotective effect by inhibiting the RSK2 and MSK1 genes, both of which are involved in tumor progression and suppression of the NF-kB signaling pathway activity, as shown in a previous study that assessed the effect of KPF in the inhibition of carcinogenesis induced by ultraviolet light in the skin of mice [38]. Here, RPS6KA3 is linked to neoplasm.