Quercitin also exerted its activity towards NF-κB during in vivo studies: treatment with this compound abrogated induction of oral adenocarcinoma in Syrian hamster buccal pouches with dimethylbenzanthracene by promoting apoptosis of tumor cells and downregulating expression of NF-κBp50 and p65 [261]. The gene discussed is NFKB1; the disease is neoplasm.