TIMP1 and Hepatic fibrosis: Moreover, TIMP1 serum concentration serves along hyaluronic acid and procollagen type 3 N-terminal propeptide (PIIINP) to calculate the Enhanced Liver Fibrosis (ELF) score for advanced liver fibrosis assessment (ELF ≤ 9.8 to rule out advanced LF, ELF > 11.3 to rule in advanced LF) [242].