No association has been found between ABCG2 expression and clinicopathological parameters [56], or between the expression of ABCG2 protein (basolateral, apical or cytoplasmatic) and age, sex, WHO performance status, location of the primary tumour, number of metastatic sites or liver or lung metastases in colorectal cancer [58]. This evidence concerns the gene ABCG2 and neoplasm.