To examine whether the transcriptional changes induced in the thyroid by αPD-1 converge with changes in biological pathways due to previously established forms of immune thyroid disease, we used the gene expression omnibus (GEO) to obtain transcriptomes of interleukin-1β-treated human thyroid cells, interferon gamma-treated human thyroid cells, and Graves’ disease mouse model thyroid tissues [14,15]. The gene discussed is IFNG; the disease is Graves disease.