DiLorenzo et al., who assessed multiple biomarkers of myocardial fibrosis for the detection of right ventricle remodeling after ToF surgical repair, amongst which was also Gal-3, concluded that only matrix metalloproteinase-1 (MMP-1), a marker of several common congenital cardiac and vascular anomalies, can really be taken into consideration [108,109]. This evidence concerns the gene LGALS3 and Myocardial fibrosis.