In one study, a decreased proportion of CD8+ T cells expressing CD107a, a marker of degranulation, in response to the N peptide pool stimulation, and a faster decline in the frequency of N-specific interferon-γ-producing CD8+ T cells were observed in patients with LC after 4 months of COVID-19 onset [187]. The gene discussed is CD8A; the disease is laryngotracheoesophageal cleft.