On the contrary, other studies have reported a plethora of autoantibodies in LC, including elevated ANA antibodies (e.g., anti-U1-snRNP and anti-SS-B/La), antineuronal antibodies, anti-IFN antibodies, autoantibodies against ACE2, the angiotensin II AT1 receptor, the angiotensin 1–7 MAS receptor, β2-the adrenoreceptor and the muscarinic M2 receptor [146,190,194,195,197,247]. This evidence concerns the gene CHRM2 and laryngotracheoesophageal cleft.