BD was associated with decreased RV expression of SERCA2A (p = 0.003), PLB (p = 0.084), and RyR2, all implicated in calcium translocation from the cytosol into the sarcoplasmic reticulum, with decreased expression of CACNA1C, a voltage-dependent calcium channel mediating calcium influx into the cell. The gene discussed is RYR2; the disease is Behcet disease.