In comparison to NS, we found significantly higher levels of TGF-beta1 (p < 0.001), IGF-1 (p < 0.001), bFGF (p < 0.001), PDGF-BB (p = 0.002) and G-CSF (p = 0.04) in HPS. This evidence concerns the gene FGF2 and Hermansky-Pudlak syndrome.