Although our study has limitations, as it would have been of great importance to investigate the death by apoptosis of human eosinophils differentiated in vitro or obtained from BALF of asthmatics patients, beyond the frequency of CD11c+CD11b+ cells in the peripheral blood and in the BALF of asthmatics patients, our study adds new clues about the pro-inflammatory role of IL-22 in allergic asthma. The gene discussed is ITGAM; the disease is allergic asthma.