TNF and metabolic dysfunction-associated steatotic liver disease: Still, according to genetic studies, human genes implicated in the replication and pathogenesis of SARS-CoV-2 are positively regulated in NAFLD, with increased activation of the JAK (Janus kinase)/STAT (signal transducers and activators of transcription) signaling pathway inducing overexpression of the interferons encoding genes, or the IL-6 overexpression occurring via tumor necrosis factor (TNF) and nuclear factor kappa B (NF-κB) signaling pathways.