P4HB and deep vein thrombosis: As shown in Figure 1A, nine-week-old mice were selected randomly and divided into four groups: the sham group (PBS), the DVT group (PBS), the DVT and PDI inhibitor group (5 mg/kg/day, three times a week for 3 weeks), and the DVT and GRP94 inhibitor (15 mg/kg/day, 10 consecutive days).