Focusing on gliomas of adults being allocated to astrocytomas, oligodendrogliomas, and glioblastomas, the main molecular hallmarks are as follows [1]: astrocytomas harbor isocitrate dehydrogenase (IDH) 1/2 mutations; and oligodendrogliomas harbor loss of 1p and 19q (1p/19q) combined with IDH1/2 mutations. Here, IDH3A is linked to oligodendroglioma.