PRMT5 and soft tissue sarcoma: A subsequent analysis of a TCGA dataset of soft tissue sarcoma samples (Firehose Legacy, n = 251) revealed that the mRNA expression levels of the other LUBAC components (HOIP and HOIL-1L) and those of PRMT5, the activity of which is modulated by SHARPIN, were not significantly associated with OS (Figure S9A–C).