With the exception of VAESBJ (epithelioid sarcoma), HT1080 (fibrosarcoma), and SW872 (liposarcoma) cells, the expression level of the SHARPIN mRNA in the other sarcoma cell lines was higher than that in HDF, although it was also expressed at a high level in 293T and HeLa cells (Figure 3A). The gene discussed is SHARPIN; the disease is sarcoma.