TNF and neoplasm: Similarly, a high tumor expression of TNF-α (median OS 7.4 vs. 16.2 months, p = 0.0033; HR = 0.6706, 95% CI = 0.5158–0.871, p = 0.0028) or CXCR4 (median OS 6.3 vs. 12 months, p = 0.0012; HR = 0.7221, 95% CI = 0.5855–0.8959, p = 0.0027) correlated with a better prognosis than negative/low tumor expressions (Figure 3B,C).