FLT4 and cholangiocarcinoma: Suksawat et al. investigated the levels of eNOS and phosphorylated eNOS (P-eNOS), along with their upstream regulators VEGFR3, VEGFC, EPHA3, and ephrinA1, in the Opisthorchis viverrini (Ov)/N-nitrosodimethylamine (NDMA)-induced hamster model of CCA and human CCA [117].