EPAS1 and hepatocellular carcinoma: EPHA2: Wu et al. aimed to investigate the expression of hypoxia-inducible factor-2α (HIF-2α), VEGF-A, EPHA2, and MVD in residual HCC after treatment with high-intensity focused ultrasound (HIFU) ablation to assess their association with tumor recurrence and growth in HepG2 xenograft mice [70].