SOX2 and urinary bladder cancer: Lnc-LBCS was shown to inhibit the self-renewal and chemoresistance of bladder cancer stem cells through the epigenetic silencing of SOX2, which was partly through H3K27me3 deposition facilitated by binding the EZH2 component of PRC2 and hnRNPK to the SOX2 promoter via triplex-DNA formation.