In addition to the aforementioned examples of linc-YY1/YY1 and GAS5/GR, where lncRNAs regulate transcription factor binding to chromatin, the MAGI2-AS3 lncRNA was found to exert tumor-suppressive and anti-angiogenic activities in clear cell renal cell carcinoma by interacting with and reducing the enrichment of the HEY1 TF at the ACY1 promoter region [183]. This evidence concerns the gene GAS5 and neoplasm.