SOX2 and central nervous system cancer: Results from in silico analysis of dataset GSE50161 showed a positive correlation between WDR82 and the expression of SOX2, (Supplementary Figure S5C), a glioma stem cell determinant [41], and one of the genes decreased in Figure 2B. ChIP-seq results from SJ-GBM2 cells show that WDR82 knockdown causes promoter H3K4me3 reduction at the SOX2 gene (Supplementary Figure S5D).