Besides LMP1 activation of the mTORC1/NFκB pathway in NPC, LMP1 is also capable of activating the PI3K/mTOR/AKT pathway, bringing about an epithelial-to-mesenchymal transition (EMT) and contributing to metastasis in EBV-infected NPC [73]. Here, AKT1 is linked to nasopharyngeal carcinoma.