By applying ICC analyses, we have found, in certain GC, the expression of tumor markers or a combination of them, including epithelial markers (AE1/AE3, KL-1, EpCAM, E-cadherin), macrophages markers (CD11b, CD68, CD163), mesenchymal marker (vimentin), and prostate tumor marker (PSMA), as well as cancer-related markers (AMACR, and TERT) helping PGCC identification. This evidence concerns the gene CD68 and intrahepatic cholangiocarcinoma.