By using the combination of tumor cytomorphology and ICC showing the presence of tumor-like markers, either EMT markers (epithelial+/vim+), PSMA, AMACR, or TERT, we found 50 PGCC from 22 prostate cancer patients, with an average number of 2.3 (range from 1 to 10) (see Table 3 and Table S1). The gene discussed is AMACR; the disease is Familial prostate cancer.