NCT05563545, a single-arm clinical study, is instead recruiting cases with recurrent or refractory CD19 positive ALL to evaluate the safety, dose, tolerance, and pharmacokinetic characteristics of CARNK-CD19 (SNC103) and also define the effectiveness, the immunogenicity of the product, and the correlation between the changes in cytokines after infusion and CRS and ICANS. The gene discussed is CD19; the disease is acute lymphoblastic leukemia.