IL2RG and precursor B-cell acute lymphoblastic leukemia: Their results suggest that FLT3-specific CAR NK cells exhibit high and selective cytotoxic activity against established and primary B-ALL cells in vitro, and in a NOD/SCID IL2Rγ-null mouse xenograft model of B-ALL, a remarkable inhibition of disease progression was observed, thus demonstrating high antileukemic activity in vivo [188].