STAT1 tends to respond to interferons (IFNs), regulating gene expression involved in multiple anticancer processes such as growth arrest, apoptosis, and immune surveillance; however, STAT1 has also been reported as an oncogene in serous papillary endometrial cancer, so the role of tumor suppressor of STAT1 is controversial and may be tumor-specific. Here, STAT1 is linked to neoplasm.