Among these, TAN-1 can be considered as a pro-tumor factor, being characterized with a high expression of genes encoding for vascular endothelial growth factor A (VEGFA), urokinase plasminogen activator, which has a role in metastasis formation, and galectin 3 (LGALS3), which mediates the proliferation and stemness of cancer cells [155,156]. Here, VEGFA is linked to cancer.