MYCN and neuroblastoma: Nevertheless, the TH-MYCN murine model—as well as derived modified models (e.g., TH-MYCN/Mdm2+/−, TH-MYCN/TH-Cre/Casp8flox/flox, LSL-MYCN; Dbh-iCre, TH-MYCN/Trp53KI/KI), which can overcome some issues associated with the original TH-MYCN mice—are extensively utilized in various fields of neuroblastoma research.