CASP8 and melanoma: In addition, Muller et al. performed a bioinformatic analysis of TCGA data and, according to their analysis, Caspase-8 expression is higher in renal carcinoma, gastric adenocarcinoma, hepatocellular carcinoma, glioblastoma, lung adenocarcinoma, urothelial carcinoma, prostate adenocarcinoma and melanoma [10].