TGFB1 and coronary artery disorder: We also examined the expression of TGF-β in the coronary vasculature and showed increased immunolabelling of TGF-β1 in the tunica media of the intramural coronary arteries in the HCM cats (Figure 6C), and this may be related to intramural coronary artery disease (IMCD), a condition commonly recognised in HCM [73].