Glutaminolysis, an abnormal activation mediated by glutaminase 1 (GLS1), promotes Th17 and γδ T17 (IL-17A-producing γδ T cell) cell differentiation by enhancing histone H3 acetylation of the IL17A promoter, leading to an immune imbalance and the development of psoriasis [114]. This evidence concerns the gene GLS and psoriasis.