As we already demonstrated in the 3-year follow-up, the prognostic significance of elevated CRP level independent of classical CV risk factors, such as age, male sex, elevated BMI, smoking, the presence of diabetes mellitus, hypertension, and hyperlipoproteinemia, remained in the 10-year follow-up [3-year follow-up: HR: 1.77; 95% confidence interval: 1.16–2.72; 10-year follow-up: HR:1.49; 95% confidence interval: 1.16–1.91) [21]. This evidence concerns the gene CRP and hypertensive disorder.