VWF and acute kidney injury: Finally, in a previously mentioned study by Reuken et al., patients with overt systemic inflammation and bacterial translocation had higher levels of VWF, which correlated with leukocytes blood count, C Reactive Protein (CRP) and LBP serum concentrations, as well as acute kidney injury during follow-up, also being predictive of liver-related death and 2-year transplant-free survival [129].