AR and major depressive disorder: In terms of FXAND, 20 PM allele carriers (66.7%) were diagnosed with depression, with the likelihood of depression being significantly reduced for carriers of PM alleles with greater AR-Sb (p = 0.02, Figure 4a) or marginally significant for carriers of PM alleles with higher AR-mPCR (p = 0.06, 335 Figure 4b).