The analysis of GPR41-ir myenteric neurons showed a reduction in CTCF of 29.8% in the Colitis group (541,127 ± 35,467) when compared to the Sham group (771,025 ± 80,560; p < 0.05) and an increase of 37.0% in the Butyrate group (859,471 ± 39,029) when compared to the Colitis group (p < 0.005) (Figure 10A). Here, FFAR3 is linked to colitis.