FBN1 and dissection: According to the 2010 Ghent revisited criteria, the diagnosis of MFS is possible in the presence of (A) aortic root dilatation/dissection + ectopia lentis; (B) aortic root dilatation/dissection + FBN1 mutation; (C) ectopia lentis + FBN1 mutation (known to have been previously associated with aortic root dilatation in the literature, or present in the family) [4].