In addition, hyponatremia has been reported in 9.1 to 51.8% of COVID-19 patients and includes several mechanisms, such as a syndrome of inappropriate antidiuretic hormone secretion, sodium loss due to diarrhea, reduced sodium intake, or use of diuretic therapy, as reviewed elsewhere [38], and is a prognostic factor for COVID-19 progression [39]. The gene discussed is AVP; the disease is Hyponatremia.