Chen et al found that upregulated ACLY can induce resistance to docetaxel, which is c9elated with worse tumor relapse-free survival in BRCA patients.[15] Wu et al found that the overexpression of AKR1B1 can activate NF-κB, thus promoting tumorigenicity and metastasis of basal-like BRCA.[16] However, few scientists have reported the effect of senescence-relevant lncRNAs (SRlncRNAs) in predicting clinical prognosis and efficacy of immunotherapy of BRCA. Here, NFKB1 is linked to neoplasm.