Moreover, among genes that were the most upregulated by miR-662 in MDA-MB-231 cells (Fig. 6a), we identified CEMIP (cell migration-inducing hyaluronidase 1), which has previously been shown to facilitate BC cell migration and proliferation through different signalling pathways including EMT, Wnt/ β-catenin, MEK/ERK and PI3K/Akt [48], and GALTN7, which promotes proliferation and invasion of different cancer cell types, including glioma, papillary thyroid carcinoma and cervical carcinoma cells [70–72]. The gene discussed is MAP2K7; the disease is central nervous system cancer.