GUCY2D and Leber congenital amaurosis: These include TRPM1-congenital stationary night blindness [18], CRB1-RP [19, 20], CNM4 Jalili syndrome [21], retinal degeneration in Usher Syndrome ([22]; NCT05158296; NCT04765345), and other forms of LCA including GUCY2D-LCA (LCA1) (ref. [23]) and AIPL1-LCA (LCA4) (ref. [24]).