ABCC8 and non-small cell lung carcinoma: We felt this pertinent as recent studies have concluded that the oncogenic activities of SUR1 in non-small cell lung carcinoma (NSCLC) are independent of KATP channel activity [66, 67], and SUR1 is reported to have a supplementary role in regulating the activity of an ATP-sensitive, non-selective ion channel in astrocytes [68].