Univariate analysis revealed following factors as significant negative predictors for DFS: lymph node metastasis (HR 3.291, p = 0.001), UICC stage III (HR 9.446, p = 0.002), Kras mutation (HR 8.938, p < 0.001) and strong TGM2 expression (HR 10.396, p < 0.001). Here, KRAS is linked to metastatic malignant neoplasm in the lymph nodes.