KCNQ1OT1 and diabetes mellitus: Long-stranded non-coding RNA KCNQ1OT1 is associated with the pathophysiological mechanisms of various complications of diabetes [13, 95], recent studies confirm that the KCNQ1OT1/miR-214/caspase-1 signaling pathway may be a novel mechanism for the progression of diabetic corneal endothelial lesions and that KCNQ1OT1 has the potential to be a new therapeutic target [96].