IL1RN and acute respiratory distress syndrome: A Genome-wide association studies pointed out several candidate genes were related to the development of ARDS, including the interleukin 6 (IL6), interleukin 10 (IL10), interleukin 1 receptor antagonist (IL1RN), vascular endothelial growth factor A (VEGFA; also known as VEGF), angiotensin-converting enzyme (ACE), soluble mannose-binding lectin 2 (MBL2) and visfatin (NAMPT) [12].