Confocal analysis showed that H1299 NSCLC cells silenced for Sorcin, after 2 h of starvation in serum-free medium (SF) and 24 h of EGF treatment, are characterized by lower actin polymerization and a reduction of stress fiber formation compared to control siNC cells, in line with reduced cell invasion and migration ability following Sorcin silencing (Supplementary Fig. 4D). This evidence concerns the gene SRI and non-small cell lung carcinoma.