Meanwhile, Lp(a), RLP-C, ApoA1/ApoB, CRI-I (OR: 1.11, 95% CI: 1.03–1.19, P = 0.005), CRI II (OR: 1.26, 95% CI: 1.15–1.39, P < 0.001), AI (OR: 1.28, 95% CI: 1.17–1.40, P < 0.001), AIP (OR: 2.06, 95% CI: 1.38–3.07, P < 0.001), and LCI (OR: 1.01, 95% CI: 1.01–1.02, P < 0.001) were still positively correlated with the increased risk CAD severity (Table 4). The gene discussed is AIP; the disease is coronary artery disorder.