FTL and central nervous system cancer: To validate the role of FTL on M2 macrophage polarization in vivo, macrophages transfected with LV-control (M-control), LV-FTL (M-FTL) and LV-shFTL (M-shFTL) were co-implanted with GL261 glioma cells in situ in C57BL/6N mice.