Assessment of the expression of the cytokine genes in 23,261 cells in one of these data sets (13) by t-distributed stochastic neighbor embedding (tSNE) revealed that expression of the IL-1β gene in subsets of macrophages and monocytes was the most pronounced in the TME of NSCLC (Supplementary Figures S2A–C; Tables 2, 3). This evidence concerns the gene IL1B and non-small cell lung carcinoma.