TRPA1 and Pruritus: Knowing the expression profile of TRPA1 and its role as a pain chemosensor, we were interested in assessing the effect of SGE on TRPA1 by measuring TRPA1-mediated Ca2+ influx in hTRPA1-HEK293t cells and the in vivo effect of SGE on TRPA1 Allyl isothiocyanate (AITC) or MrgprA3 (CQ) receptor agonist-induced pruritus.