TGFB1 and Hepatic fibrosis: In rats, Tsai et al., (2009) have shown that injection of WJ-MSCs significantly reduced the liver fibrosis by decreasing collagen deposition, serum levels of glutamic oxaloacetic transaminase, glutamic pyruvate transaminase, and TGF-β1 and increasing mesenchymal-epithelial transition factor-phosphorylated type and hepatocyte growth factor.