KCNA1 and epilepsy: In a Kcnal−/− mouse model which mimicked the associations of human KCNA1 gene variants with epilepsy and episodic ataxia, A. muciniphila together with Parabacteroides (but not alone) protected these mice against epilepsy by decreasing systemic ɣ-glutamylated ketogenic amino acids, elevating hippocampal ɣ-aminobutyric acid (GABA)/glutamate ratios and suppressing the ɣ-glutamyl transpeptidase (GGT) activity in the feaces (Olson et al., 2018).