CRP and Stroke: Furthermore, when SII was replaced with CRP, the highest tertile of CRP was also associated with the incidence of stroke (HR, 16.1; 95% CI, 1.97–132, P = 0.009) and MACCE (HR, 2.56; 95% CI, 1.19–5.53, P = 0.017) during the long-term follow-up.